Exosome therapy for hair loss is a hot topic and we expect this therapy to reshape hair loss treatment forever.  While stem cells for hair loss have been beneficial for some patients, exosomes take the theory behind regenerative hair loss to the next level.

Exosomes are derived from stem cells and represent the newest frontier in regenerative medicine.  Regenerative medicine is still in its infancy stages and has potential in multiple disciplines including cardiac, orthopedics, pain management, and cosmetics.  Regenerative therapies for hair loss include PRP and stem cells for hair loss treatment.   Exosomes for hair loss is new and takes this concept one step further by directly messaging hair follicles to grow.

In this article we provide the reader insight into this exosome hair loss therapy.  Ideally, we would have stem cells capable of restoring hair loss without more invasive therapies like hair transplants.

What are exosomes?

Exosomes are tiny extracellular vesicles utilized by stem cells that give them their incredible power to regenerate new tissue (including hair). These tiny nano-particles are only 1/1000th the size of a stem cell and contain over 1000 protein growth factors.  Proteins delivered in the exosomes provide cellular communications that signal healing, anti-inflammatory responses, and cellular growth.  In theory, exosomes can be manipulated to deliver pre-programmed messages to target cells, including hair follicles.

Current studies examining Exosome therapy for hair loss include a study in Journal of Experimental Dermatology by Kwack MH where dermal papilla exosomes were found to promote hair growth and hair generation.  Another study in Front Immunology by Zoller M found that autoimmune alopecia areata could successfully be treated by exosome therapy for hair loss.  Zhou in Biochem Biophys Res Commun found that dermal papilla cell exosomes were found to be a potential avenue for treatment for hair loss as well. 

How is the procedure performed?

​While exosomes can be harvested from most human stem cells, the most powerful ones are derived from mesenchymal stem cells utilized by ExoFlo (™).  These stem cells are used to collect up to 10 billion exosomes per milliliter with high-value cellular signals for growth. 

ExoFlo(™)  is injected in the same fashion as PRP treatments for hair loss.  The treatment can be done with 2.5 cc or 5 cc depending on the amount of hair loss.  The first step is providing local anesthesia to the desired area to numb the region.   The preparation is then injected into the scalp using the tiniest of needles just under the skin to thinning scalp areas.

The injections are spaced carefully to maximize the treatment effect with concentrated protein factors that promote hair growth.  The treatment is effective in both men and women with most patterns of hair loss. Because the preparation is acellular, the treated areas do not demonstrate any inflammation or redness post-treatment. 

In hair loss treatment, the exosomes deliver “wake up” signals to your dormant follicles and stimulate the production of new hair cells.

Final thoughts:
Hair transplant doctors NJ are embracing regenerative techniques that have the power to reshape hair loss treatment.  Exosome therapy in hair loss is used in combination with hair transplant procedures, as well as a stand-alone procedure.  Early results are promising with many patients showing hair growth in as few as 4 weeks. At Hair transplant NJ, the best hair loss doctors take pride in staying at the cutting edge of research into regenerative medicine and are always excited to share that passion with their clients!

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